产品货号：
Z34336
中文名称：
TAB2抗体
英文名称：
Anti-TAB2 Antibody (Clone#3B5)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TAB2 Antibody (Clone#3B5) |
| 指标别名 | KIAA0733;MAP3K7IP2;TAB 2;TAB2;TAK1 binding protein 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | TAB2 |
| 克隆号 | 3B5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of human TAB2 expressed in E.Coli. |
| 计算分子量 | 76KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Mitogen-activated protein kinase kinase kinase 7-interacting protein 2,also known as TAB2,is an enzyme that in humans is encoded by the MAP3K7IP2 gene.The protein encoded by this gene is an activator of MAP3K7/TAK1,which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK.This protein forms a kinase complex with TRAF6,MAP3K7 and TAB1,thus serves as an adaptor linking MAP3K7 and TRAF6.TAB2 functionally links TAK1 to TRAF6.What's more,TAB2 can act as a sensor for inflammatory signals by serving as a molecular beacon for recruitment of MEKK1(MAP3K1),which in turn mediated dismissal of the NCOR/HDAC complex and permitted derepression of AR and estrogen receptor target genes. |
| Uniprot ID | Q9NYJ8 |
| 基因名全称 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 |
| 蛋白名全称 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 |
| 推荐稀释比 | WB 1:500～1:2000 FC 1:200～1:400 ELISA 1:10000 |
相关搜索：TAB2抗体，TAB2单抗，Anti-TAB2 Antibody (Clone#3B5)